For patients & caregivers

Understand your cancer information.Prepare for the next conversation.

Clear explanations of precision oncology, what testing can and cannot tell you, and how OnKommon Twin follows the picture over time — always alongside your oncologist.

Read the patient guide Questions for your oncologist

Patients · storyline

Every life deserves every option.

What OnKommon Twin means for you and your family.

Understood
Every option
Every change
Your doctor
For years

01 / 05 · Understood

Your cancer, understood in depth.

Your oncologist chooses a testing pathway, and the changes in your tumour are read through 21 analytical layers — so the picture is as complete as it can be.

Understanding your Twin →

Before anything else

Testingcanaddinformation.Itcannotpromiseanoutcome—andyouroncologiststayswithyouateverystep.

What to expect

Before, during and aftertesting.

Before
Talk with your oncologist
Your oncologist decides whether molecular testing is appropriate and which Twin pathway fits — blood cancers use Blood 600; solid tumours use Exome, Liquid 523 or Tissue 335. Ask what the test could change, and how consent works.
During
Sample and analysis
A blood, bone-marrow or tumour-tissue sample is tested, depending on the pathway. The results are combined with information from your treating team and analysed.
After
Review with your oncologist
Your oncologist reviews and signs the report, and it is discussed at KPCIRC's Molecular Tumour Board. Your oncologist explains what it means for you.
Over six months
Follow-up
Twin keeps the findings under review for six months as new results and evidence arrive. At the end, your oncologist decides on the next step.

The patient guide

Start wherever you are

Setting expectations

What testing can — and cannot — tell you

It can

Identify changes in the tumour's DNA or RNA within what the test covers
Show whether some changes are linked by evidence to treatments or trials
Give your oncologist more information to weigh
Be revisited over time as new information arrives (with Twin)

It cannot

Guarantee that a treatment will work
Find something actionable in every case
Replace your oncologist's judgement
Capture every part of a tumour from one sample

OnKommon for patients

Twin is the pathway for patients

AVATAR is a separate research programme — not a way to choose treatment.

Longitudinal intelligence

OnKommon Twin

Your oncologist chooses the testing route; your Twin then follows every result, scan and symptom — and a genetic read every three months.

Understand your Twin

Exploratory research

OnKommon AVATAR

A biological investigational plan that studies your tumour's mutations in a living model, with your oncologist and KPCIRC's tumour board.

Discover AVATAR

Your oncologist stays in charge.

Every Twin report is reviewed and signed by your treating oncologist and discussed at KPCIRC's Molecular Tumour Board. Your oncologist makes every treatment decision with you.

How sign-off works

Questions for your oncologist

Questions you might want to ask

01Which testing pathway do you think is appropriate for my cancer, and why?
02What could this test tell us — and what can it not tell us?
03If a finding is uncertain, how will we decide what it means?
04Could any result have implications for my family? Would I be offered genetic counselling?
05If a treatment option or trial is identified, how will we decide whether it is right for me?
06How will we follow changes over the next six months, and what happens after that?
07Who else will review my results, and how is my information kept private?

Practicalities

Privacy and consent

FAQs

Questions patients often ask

Can I order OnKommon Twin myself?

Molecular testing and interpretation work best when planned with your treating oncologist, who chooses the appropriate pathway and makes treatment decisions. You are welcome to enquire, and we will explain how to involve your oncologist.

Will genomic testing find a treatment for me?

Testing looks for findings linked to therapies and clinical trials — and the Twin keeps looking as the evidence grows. Your oncologist discusses every finding with you and decides what it means for your care.

What is a variant of uncertain significance (VUS)?

A change in a gene whose effect is still being understood. The Twin keeps it on watch, and its interpretation is updated as the evidence grows.

Could a result affect my family?

Some findings may be inherited. These need confirmation and genetic counselling before they are treated as a hereditary diagnosis.

What is AVATAR?

AVATAR is a biological investigational plan: your tumour's drivers are carried into a living fruit-fly model and screened against candidate drugs. Your oncologist weighs the results with everything else they know.

How do I share my reports?

Through a secure route set up with your care team — or by upload or WhatsApp during longitudinal monitoring. Website forms are for enquiries only.

Ready to talk about a suitable pathway?

Send a general enquiry — no medical details needed. We'll explain how to involve your oncologist.

Enquire about a suitable pathway Understanding Twin