Research & academia
Computational oncology,investigational biology.
Research & academia · storyline
Investigate the biology behind the variant.
OnKommon AVATAR is a biological investigational plan — and Twin is a documented analytical architecture.
01 / 06 · Interpret
Read the tumour genome.
How we work
Fromthetumour'sgenometoitsbiologyinalivingmodel—evidenceyoucaninvestigate.
Choose a context
Where are you coming from?
Pharma & biotech
Translational questions around molecular targets, resistance and candidate therapies.
ExploreDiagnostics
Interpretation and workflow partnerships around molecular testing.
ExploreClinical development
Trial intelligence and biomarker-defined research questions.
ExploreAcademic research
Computational oncology, methodology and AVATAR research collaboration.
Explore
Two offerings
Research relevance of each
OnKommon AVATAR
Two evidence streams for translational questions
OnKommon Interpreter
Computational- 01Tumour genome
- 02Variant analysis
- 03Evidence interpretation
- 04Molecular findings
What does the genomic evidence show, and how strong is it?
AVATAR Discovery Process
Experimental- 01Selected tumour mutations
- 02Engineered fruit-fly model
- 03Drug screening
- 04Experimental observations
What responses were seen when candidate drugs were screened in the model?
Integrated report
Molecular findings, screening observations, limitations and considerations for assessment.
KPCIRC Molecular Tumour Board
Reviews findings, interpretation, clinical context and therapeutic implications.
Treating oncologist
Finalises and signs the report. Retains ultimate clinical ownership of treatment decisions.
How collaboration works
Scoped together, governed from the start
- 01
Initial enquiry
Tell us your organisation, role and research question. Patient data and genomic files are exchanged later, through a secure channel.
- 02
Scoping discussion
Define the question, data inputs, deliverables, roles, governance and timelines together.
- 03
Confidentiality and data governance
A secure channel and the appropriate confidentiality, data-access and consent arrangements are put in place before any sensitive information is exchanged.
- 04
Ethics and approvals
Where applicable, ethics committee approval and an approved protocol govern participation, sample use, consent and eligibility.
- 05
Study conduct and reporting
Work proceeds under the agreed protocol, and publication terms are agreed in advance.
Discuss a research collaboration.
Tell us your organisation and broad question. Please do not send confidential or patient data through the website.