04 · 21 proprietary layers
Layer 12 of 21 · Clinical integration
Imaging Integration Radiology and imaging biomarkers.
Why it's needed
How can relevant imaging findings or changes contribute to the evolving picture?
What it draws on
2 of 8 evidence domains.
What it produces
Imaging-related findings and longitudinal comparisons where supported.
Why it's essential
Layer 12 of 21.
1 · What it does
What Imaging Integration does
Imaging is central to how cancer is staged and followed. Imaging Integration is intended to bring relevant radiology findings, and how they change, into the same view as the molecular results.
2 · Scientific question
The question it addresses
How can relevant imaging findings or changes contribute to the evolving picture?
Intended function
Explain how imaging reports or data may be brought into the Twin context.
3 · Data inputs and required context
What it draws on
- 04 Imaging integration
- 03 Clinical context
Radiology findings supplied with the case.
4 · Scientific basis
The science behind it
Scientific basis
Imaging can be integrated as radiology reports (text), as structured measurements under formal response criteria, or as image-derived quantitative features. Each has different reliability, and each requires different inputs.
5 · Output and evidence sources
What it produces
Main output
Imaging-related findings and longitudinal comparisons where supported.
Output type
- Clinical-context integration. Depends on clinical information supplied by the treating team.
6 · Why it\u2019s essential
How it powers the Twin
Adds imaging change to the longitudinal view and gives Kinetix serial data to work with.
Report section
7 · Why it\u2019s needed
What it changes — for doctors, patients and researchers
Patients & caregivers
Shows how scans and molecular tests are considered together.
Patient & Caregiver8 · Dependencies and limitations
Limitations
- Comparisons across different scanners, protocols or modalities need caution.
9 · Review and uncertainty
How the output is handled
Output status
An AI-assisted analytical output presented as structured findings for clinician review. It becomes part of a report only after the treating oncologist has reviewed and signed it.
How uncertainty is communicated
Each imaging item states its source (report, measurement or image) and date.
10 · Claim boundary
What this layer does not establish
It does not provide an independent radiological read of images.
The treating oncologist owns every decision. Every Twin report is reviewed and signed by the treating oncologist, then taken to KPCIRC's Molecular Tumour Board.
KPCIRC sign-off process