04 · 21 proprietary layers
Layer 19 of 21 · Longitudinal intelligence
EvidencePulse Continuous evidence monitoring.
Why it's needed
What relevant evidence has changed since the previous review?
What it draws on
2 of 8 evidence domains.
What it produces
Evidence updates or notifications consistent with the live workflow.
Why it's essential
Layer 19 of 21.
1 · What it does
What EvidencePulse does
Oncology evidence moves quickly: new approvals, updated guidelines, new trials and reclassified variants. EvidencePulse is intended to identify relevant changes in evidence since the previous review, so the treating team can decide whether reassessment is warranted.
2 · Scientific question
The question it addresses
What relevant evidence has changed since the previous review?
Intended function
Explain the actual evidence sources, update cadence and method for surfacing relevant changes.
3 · Data inputs and required context
What it draws on
- 08 Evidence ecosystem
- 01 Molecular & genomic
The case's existing findings, compared against updated evidence sources.
4 · Scientific basis
The science behind it
Scientific basis
Evidence monitoring re-checks findings against updated sources at a defined interval or trigger. Its value depends on which sources are monitored and how often.
5 · Output and evidence sources
What it produces
Main output
Evidence updates or notifications consistent with the live workflow.
Output type
- Evidence-linked interpretation. Connects a finding to published or curated evidence, which has a source and a date.
- Twin workflow function. Part of how the Twin is created, reviewed or updated, rather than an analytical result.
6 · Why it\u2019s essential
How it powers the Twin
Prompts reassessment within the longitudinal view when new evidence arrives.
Report section
7 · Why it\u2019s needed
What it changes — for doctors, patients and researchers
Patients & caregivers
Knowledge changes over time; the Twin is designed to revisit the evidence.
Patient & Caregiver8 · Dependencies and limitations
Limitations
- Evidence sources are checked on a published cadence, and each update shows when it was checked.
- A change in evidence is surfaced for review; it does not change the patient's care by itself.
9 · Review and uncertainty
How the output is handled
Output status
An AI-assisted analytical output presented as structured findings for clinician review. It becomes part of a report only after the treating oncologist has reviewed and signed it.
How uncertainty is communicated
Updates state the source, its date and the date it was checked.
10 · Claim boundary
What this layer does not establish
It does not guarantee that every relevant new publication or approval is captured.
The treating oncologist owns every decision. Every Twin report is reviewed and signed by the treating oncologist, then taken to KPCIRC's Molecular Tumour Board.
KPCIRC sign-off process