04 · 21 proprietary layers
Layer 15 of 21 · Action and continuity
TwinBirth Creation of the patient's digital twin.
Why it's needed
What is the starting information set and how is the initial Twin established?
What it draws on
5 of 8 evidence domains.
What it produces
A baseline structured view, with the inputs used and missing information identified where supported.
Why it's essential
Layer 15 of 21.
1 · What it does
What TwinBirth does
Every Twin starts somewhere. TwinBirth is intended to establish the baseline Twin from the data available at the start of the journey — Day 0 in the six-month journey — and to record what information is missing.
2 · Scientific question
The question it addresses
What is the starting information set and how is the initial Twin established?
Intended function
Describe the baseline integration and documented configuration of a Twin from the available case data.
3 · Data inputs and required context
What it draws on
- 01 Molecular & genomic
- 03 Clinical context
- 04 Imaging integration
- 06 Treatment exposure
- 07 Patient factors
The testing-pathway result plus the clinical, imaging and treatment information supplied at baseline.
4 · Scientific basis
The science behind it
Scientific basis
This is a data-integration and configuration step rather than an analysis. A baseline representation is only as complete as the inputs available at that moment.
5 · Output and evidence sources
What it produces
Main output
A baseline structured view, with the inputs used and missing information identified where supported.
Output type
- Twin workflow function. Part of how the Twin is created, reviewed or updated, rather than an analytical result.
6 · Why it\u2019s essential
How it powers the Twin
Creates the reference point that every later update, comparison and decision record builds on.
Report section
7 · Why it\u2019s needed
What it changes — for doctors, patients and researchers
Clinicians
A clear statement of what the Twin was built from and what it lacks.
Doctor & Clinical TeamPatients & caregivers
The Twin is a structured model of the available information, not a copy of the person.
Patient & Caregiver8 · Dependencies and limitations
Limitations
9 · Review and uncertainty
How the output is handled
Output status
An AI-assisted analytical output presented as structured findings for clinician review. It becomes part of a report only after the treating oncologist has reviewed and signed it.
How uncertainty is communicated
The baseline lists the inputs used and the inputs that were unavailable.
10 · Claim boundary
What this layer does not establish
It does not create a complete digital copy of the patient or the cancer.
The treating oncologist owns every decision. Every Twin report is reviewed and signed by the treating oncologist, then taken to KPCIRC's Molecular Tumour Board.
KPCIRC sign-off process