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Newly diagnosedReports arriving, no plan yetAlready tested elsewhereYou have results you cannot readOn treatment nowYou want to know it is workingOr
Finished treatmentWatching for anything left behindWorried about familyInherited risk, and relativesWanting a second opinionA decision you are unsure aboutDecide
Blueprint CareThe flagship decision report and a dedicated clinical teamSignalOne free question answered on WhatsApp within four hoursNavigationRecords you already have, turned into a clarity timelineDecipherInterpretation of sequencing already done elsewhereTest: solid tumour
All Signature testsEvery panel compared, side by sideSignature STb33 genes from a blood drawSignature STb O118 genes from blood, including fusionsSignature STb O+523 genes, with TMB, MSI and pharmacogenomicsSignature STt OComprehensive profiling from a tissue blockTest: blood cancer
Signature BML+Myeloid, 600+ genes, with MDS and MPN overlapSignature BLL+Lymphoid, 600+ genes, with Philadelphia-like detectionSignature CustomDesigned around one question when neither family fitsMonitor
SentinelSerial monitoring while treatment is runningSentinel SolidctDNA monitoring for solid tumoursClearMolecular residual disease surveillanceClear SolidTumour-informed surveillance for solid tumoursClear BloodResidual disease surveillance after blood cancer treatmentProtect
HeritageInherited risk, assessed properlyHeritage CoreA broad inherited-risk assessmentHeritage AdhocFocused testing for named relativesCancer DictionaryWhat is discussed in your specific cancerReference
Cancer DictionaryOne structured entry per cancer typeBiomarker LibraryOne page per marker, in plain languagePatient ResourcesGlossary, guides and how to use themWatch, read and ask
Video LibraryShort explainers, captioned and translatedJourneysFour composites showing how a decision gets madeCase studiesNine situations and the test that fits eachFAQThe questions we are asked mostServices · the whole catalogue
What each one is, who it is for, when it applies, and what it cannot do. In one table, so you do not have to open six pages to compare two things.
What, who, when
Six product families, fourteen ways in. The table below is the whole catalogue in one place, so the question “what is the difference between these two” does not require opening six pages.
| Service | What it is | Who it is for | When | Sample | What you get |
|---|---|---|---|---|---|
| Signal | One question, answered by a person on WhatsApp | Anyone, at any stage | Any time. Start here if unsure | None | A human-guided reply within four hours, free |
| Navigation | Your existing records turned into a clarity timeline | Anyone whose paperwork has outgrown them | Before a decision, or before a second opinion | Existing records | A timeline and roadmap you can hand to any clinician |
| Blueprint Care | The decision report and a dedicated clinical team | Anyone facing a treatment decision | At diagnosis, or when treatment changes | Comes with a Signature test or Decipher | A ranked, evidence-tiered plan signed by a tumour board |
| Decipher | Interpretation of sequencing done elsewhere | Anyone already tested but not answered | When you hold a report you cannot act on | Your existing data. No new sample | Full interpretation and board sign-out, without resequencing |
| Decipher Plus | Topping up only the gaps, then interpreting | Where an earlier panel missed something material | When prior testing was too narrow | Existing data plus a targeted top-up | The same report, with the gap filled rather than the test repeated |
| Signature STb | A 33-gene panel from a blood draw | A focused first molecular question | Before a treatment decision | Blood | Variants, therapy matching and a signed decision report |
| Signature STb O | A 118-gene panel from a blood draw | Broader profiling without tissue | Before a treatment decision | Blood | Wider coverage including fusion genes |
| Signature STb O+ | A 523-gene comprehensive panel | When the whole molecular picture matters | Advanced disease, or a complex decision | Blood | Comprehensive profiling with TMB, MSI and pharmacogenomics |
| Signature STt O | Comprehensive profiling from tissue | Where a tumour block already exists | When tissue is available and adequate | An existing FFPE tissue block | Tissue-based comprehensive profiling |
| Signature BML+ and BLL+ | Profiling for blood cancers, 600+ genes | Myeloid and lymphoid disease | At diagnosis, and again at relapse | Blood or bone marrow | Leukaemia-specific molecular characterisation |
| Sentinel | Serial monitoring while treatment runs | Anyone on active treatment | Every few weeks or months, alongside scans | Blood, repeated | A trend line showing response and emerging resistance |
| Clear | Surveillance after curative-intent treatment | Anyone who has finished treatment | On a schedule, for years afterwards | Blood, repeated | Molecular residual disease surveillance |
| Heritage Core | A broad inherited-risk assessment | The person diagnosed, or someone at risk | When a cancer looks like it runs in the family | Blood or saliva | Germline result with genetic counselling |
| Heritage Adhoc | Focused testing for named relatives | Relatives of someone with a known alteration | Once the family alteration is identified | Blood or saliva | A yes or no on one specific variant, with counselling |
What each service costs is discussed at a free consultation rather than published here, because the right tier depends on the question being asked and a bigger panel is not automatically the better one. Signal and the consultation itself are free, and we will tell you when a test would not change anything before you commit to it.
Choosing between them
Sentinel watches during active treatment: is this working, is resistance emerging. Clear watches after treatment given with curative intent: is anything left, is it coming back. Same technology, different question, different schedule.
Signature generates new sequencing. Decipher interprets sequencing that already exists. If you have been tested properly and recently, Decipher is usually the cheaper and faster route to the same answer.
It depends on the question, not on the budget. A focused question about a well-defined driver may be answered by 33 genes. A complex case with few standard options is where 523 genes earns its cost. Our consultation exists to work that out honestly.
Heritage tests what you inherited, from blood or saliva, and the answer concerns your relatives as much as you. Signature tests what the tumour acquired. They answer different questions and one does not substitute for the other.
Blood is easier and repeatable but depends on the tumour shedding enough DNA. Tissue is the conventional reference but needs an adequate sample and cannot be repeated casually. In several cancers the two are used together rather than sequentially.
Sometimes not. In some cancers and at some stages, molecular profiling will not change what happens next, and we would rather tell you that at a free consultation than take your money to confirm it.
How they fit together
Stage 01 of 06
Interpret the evidence already available, reconcile the reports, and make the important unknowns visible before decisions build on incomplete information.
Next questionCreate a reliable starting point.
Stage 02 of 06
Use molecular profiling when the next decision depends on a more precise view of the disease, rather than ordering every possible test. A bigger panel is not automatically the better one.
Next questionChoose the right level of evidence.
Stage 03 of 06
Translate interpreted evidence into a decision-ready discussion: options, constraints, uncertainties, and the questions to put to the treating team.
Next questionMove from information to an informed plan.
Stage 04 of 06
Keep interpreting the evidence as treatment progresses and new results change the picture, rather than treating the original interpretation as permanently fixed.
Next questionRevisit the evidence as the situation evolves.
Stage 05 of 06
At meaningful decision points, revisit the evidence when scans, progression, resistance, toxicity or new clinical information change the original assumptions.
Next questionReframe the next decision with current evidence.
Stage 06 of 06
Carry forward what remains useful beyond the immediate treatment phase, while new questions emerge around surveillance, family risk and future decisions.
Next questionKeep the pathway open to new questions.
Available at any point
Signal is a free entry point for a question, a report, or a second look. It is not tied to one stage of the pathway, and it costs nothing.
Next questionAvailable throughout the journey.
Available at any point
A free consultation creates space to frame the question, understand what is missing, and decide what kind of work is actually appropriate. Sometimes the answer is that no test would change anything, and we will say so.
Next questionAvailable throughout the journey.
Illustrative. People enter at different points, skip stages, or revisit an earlier question as evidence changes. No duration or sequence is implied.
Stated plainly
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